Abstract
Antihistamines are a class of drugs that inhibit the effects of histamine, a key mediator in allergic reactions and inflammation. They are widely used to treat conditions such as allergic rhinitis, urticaria, anaphylaxis, and motion sickness. This article provides a comprehensive overview of the pharmacology of antihistamines, including the different generations, receptor selectivity, mechanisms of action, and side effects. It also discusses current and emerging therapeutic applications and highlights challenges in clinical use and drug development.
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