Abstract
Understanding the pharmacokinetics and toxicity profiles of anticancer drugs is critical for optimizing cancer treatment and minimizing adverse effects. This article reviews the key pharmacokinetic parameters—absorption, distribution, metabolism, and excretion (ADME)—and their influence on the efficacy and safety of anticancer agents. It also explores common toxicities associated with chemotherapeutic and targeted therapies, mechanisms of drug resistance, and strategies to mitigate toxicity. The review aims to guide clinicians and researchers in selecting appropriate regimens and improving patient outcomes.
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