Abstract
Antifungal agents play a crucial role in treating fungal infections, particularly in immunocompromised patients. Understanding the pharmacodynamics (PD) of antifungal agents is essential for optimizing treatment regimens and improving clinical outcomes. This article provides an in-depth exploration of the pharmacodynamic principles governing antifungal therapy, including concentration- and time-dependent effects, post-antifungal effects, and resistance mechanisms. It also discusses emerging PD targets and strategies to enhance antifungal efficacy while minimizing toxicity and resistance development.
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