Abstract
Pharmaceutical excipients, once regarded as inert carriers, have evolved into essential components that influence drug formulation efficacy, stability, and delivery. Recent advances in the design and functionality of excipients have enabled the development of more complex drug delivery systems, enhancing bioavailability and patient compliance. This article reviews the current state of excipient research, focusing on innovative materials, multifunctional roles, regulatory perspectives, and emerging technologies such as nanocarriers and stimuli-responsive polymers. Emphasis is placed on the critical role excipients play in addressing formulation challenges, particularly for poorly soluble and sensitive active pharmaceutical ingredients (APIs).
All articles published in the American Journal of Pharmaceutics are open access and licensed under the Creative Commons Attribution 4.0 International License (CC BY 4.0). This license allows users to:
-
Share — copy and redistribute the material in any medium or format
-
Adapt — remix, transform, and build upon the material for any purpose, even commercially
Under the following terms:
-
Attribution — Appropriate credit must be given, a link to the license must be provided, and any changes must be indicated.
-
Authors retain full copyright of their work.
-
The journal does not restrict reuse of content, provided proper citation of the original publication is made.