Abstract
Pediatric drug formulation presents a complex challenge due to the unique physiological, developmental, and psychological needs of children. Factors such as age-specific dosing, taste masking, safe excipients, and flexible dosage forms are critical for ensuring compliance and therapeutic efficacy. This article explores key challenges in pediatric drug development and reviews advanced strategies including orodispersible tablets, mini-tablets, 3D printing, and nanotechnology-based delivery systems. Regulatory perspectives and global initiatives are also highlighted to foster innovation and standardization in pediatric pharmacotherapy.
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