Natural Products as a Source of Novel Drug Lead
PDF

Keywords

Natural products
drug discovery
bioactive compounds
pharmacognosy
metabolomics
molecular docking

Abstract

Natural products have been the cornerstone of drug discovery for centuries, offering structurally diverse and biologically active compounds. Their unique chemical frameworks, developed through evolutionary processes, provide unmatched templates for the development of novel drug leads. This paper discusses the pharmacological importance of natural products, the modern techniques used in their identification and characterization, and the challenges faced in their development. Case studies such as taxol, artemisinin, and rapamycin illustrate their impact on modern medicine. With the integration of omics technologies and AI in bioactive compound screening, natural products remain an indispensable reservoir for future therapeutics.

PDF

All articles published in the American Journal of Pharmaceutics are open access and licensed under the Creative Commons Attribution 4.0 International License (CC BY 4.0). This license allows users to:

  • Share — copy and redistribute the material in any medium or format

  • Adapt — remix, transform, and build upon the material for any purpose, even commercially

Under the following terms:

  • Attribution — Appropriate credit must be given, a link to the license must be provided, and any changes must be indicated.

  • Authors retain full copyright of their work.

  • The journal does not restrict reuse of content, provided proper citation of the original publication is made.