THE BIOLOGICAL INTERFACE ADAPTATION MECHANISM OF GRAPHENE FLEXIBLE ELECTRODES

Abstract

Graphene flexible electrodes, with their unique two-dimensional structure and excellent physical and chemical properties, have demonstrated significant advantages in the field of bioelectronic interfaces. This paper systematically explores the interface adaptation mechanism between graphene flexible electrodes and biological tissues, and conducts an analysis from four dimensions: material properties, interface interaction, biocompatibility regulation, and dynamic adaptability. Research shows that the electrical conductivity, mechanical flexibility and surface chemical modification ability of graphene jointly build the stable adaptation basis of the biological interface, while its interaction with the cell membrane, proteins and extracellular matrix determines the long-term functional stability of the electrode. By regulating the surface functional groups, conductive network structure and mechanical compatibility of graphene, dynamic synergy between electrodes and biological tissues can be achieved, providing key technical support for neural interfaces, wearable devices and implantable medical devices.