Abstract
Oxidative stress plays a significant role in the pathogenesis of many chronic and degenerative diseases. Antioxidants, which neutralize reactive oxygen species (ROS), have emerged as promising therapeutic agents in drug development. This article explores the role of antioxidants in the design of drugs for conditions such as cardiovascular diseases, neurodegenerative disorders, cancer, and aging-related ailments. It discusses natural and synthetic antioxidants, their mechanisms of action, recent advancements, challenges in clinical translation, and the future prospects of antioxidant-based drug development.
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